Research

The MPS Society has been funding cutting-edge research into MPS, Fabry and related diseases since its inception in 1982.

 

To this day, the MPS Society has spent over £12 million on research projects into these conditions, to find better treatments and care. Scientific breakthroughs and new technologies offer hope for diagnoses and treatments for those affected that was unimaginable a few years ago.

 

The sooner we can accelerate our research and take advantage of these opportunities, the quicker we can help even more people affected by MPS, Fabry or a related disease.

We invite research applications on the theme of psychological wellbeing 

The MPS Society is inviting grants for scientific or clinical research into LSD or related conditions. Following a review of its patient support, in this round of grants the society is particularly interested in receiving applications that support and/or improve the psychological wellbeing of those impacted by LSD or related conditions. While the Society will accept applications from single centres or research units, we are specifically looking for applications from applicants collaborating with other centres or units in the field.

Clinical Scientific Advisory Board (CSAC)

 

Our Clinical Scientific Advisory Committee (CSAC) consists of members of our Board of Trustees and the Society’s Patient Advocacy team. These members come from medical, healthcare or research backgrounds from a broad range of disciplines and perspectives who will consider research applications each year.

 

All proposals will be subject to a review process to ensure they meet our high standard of quality. The committee will make an informed recommendation to our Board of Trustees who hold the final decision on how we allocate research funds. 

Applications for grants will be assessed on:

  • The importance or burden of the health or care problem being studied

  • What the proposed research adds to the existing body of knowledge

  • The improvements in health and care this research is likely to lead to

  • The potential impact of the research on patients, the public and people working in health and care

  • Whether the cost of the research is reasonable and commensurate with the work involved

  • The likelihood that the research design is feasible and deliverable and answers the proposed question

We will consider applications across the breadth of metabolic medicine, but of course, will focus on MPS and related disorders.

Conflicts of interest


Both the Clinical and Scientific Advisory Committee and any external reviewers are asked to declare any conflicts of interest. Those with conflicts are not permitted to discuss or provide comment on those applications.

More information

How to apply

Current research funded

About the diseases

Contact us

 

For any questions, details of our T&Cs or to receive details on applying for a grant please contact the CSAC team by email or phone +44 (0)345 260 1087 

Research grant application process

 

The MPS Society is inviting applications for research grants in MPS, Fabry and related diseases. The grants will be awarded for a period of between one and three years but funding in years two and three will be subject to an annual review and the charitable funds being available. Members of the MPS Society’s Clinical and Scientific Advisory Committee (CSAC) will review the grant proposals. All research grant applications must meet the MPS Society’s terms and conditions of Medical Research Grants. 

Can you join the peer review panel?

We are committed to transparency and open access and applications will be sent out for peer-review. We would encourage all applicants, potential applicants or people with an interest to help us support impactful research by joining our peer review panel, if you are willing to spare a couple of hours reviewing an application please contact the peer review coordinator.

Apply​ now

 

Applications for research grants are currently open. Applications will be reviews at one of the peer review committee meetings throughout the year.  

How to apply


In order to apply you can either fill out an application form online or download a PDF form [coming soon].




Decision process


Following submission, grant applications will be reviewed internally by members of the MPS Society’s Clinical and Scientific Advisory Committee (CSAC). This committee includes trustees with a medical or scientific background, non-medical trustees and members of the MPS Society’s Support and Advocacy senior team. A shortlist of applications will then be sent for external peer review, by a panel of relevant medical experts. It should be noted these may include international experts.

The committee that makes funding recommendations meets up to six times a year and submitted applications will be considered at the next available committee slot. If for any reason you need support with the application process or think your application needs fast-tracking then please contact the committee secretariat.

We are committed to transparency and open access and applications will be sent out for peer-review.




Feedback after submission


All applicants, successful or otherwise, will receive anonymised feedback from the Clinical and Scientific Advisory Committee and where available the peer review panel.




Conditions


Detailed Terms and Conditions of Medical Research Grants, the MPS Society’s Moral and Ethical Policy for Fundraising and Public Affairs Activities and acceptance forms are attached with the application form.

Research grant payments will be made quarterly in arrears. Quarterly payments beyond the first quarter for second and third year grants will only be made after a review of the research project has been undertaken and an appraisal report received.

A final report must be submitted within two months of the end of the research grant and include:

  • A summary of the results of the research project
  • Indication of whether goals were met
  • If applicable suggestions for further research efforts needed in the field
  • A summary statement in lay language of the results of the research which will be communicated via emails and social media.

If the results are published in any scientific journals, provision of a copy of the article(s) is required.

The MPS Society requests that all acknowledgements include the following: ‘This work was supported by a research grant from the Society for Mucopolysaccharide Diseases (MPS Society) www.mpssociety.org.uk’




Supporting documents


When you submit the application you will need to include:





 

Funded research

In January 2020, the MPS Society awarded a grant to Professor Simon Heales of Great Ormond Street Hospital, London to employ a scientist for one year to evaluate a new piece of equipment that could significantly improve our ability to identify patients with lysosomal disorders such a MPS I, Pompe, Fabry and Gaucher Disease. The new technology, known as Digital Microfluidics, will be thoroughly tested by the Enzyme Laboratory at Great Ormond Street Hospital. Key aims of this study will be to document how robust and reliable the equipment is and how well it copes with large numbers of samples. At the end of the study, a recommendation will be made as to whether Digital Microfluidics is a suitable technique that could be used for incorporation into a newborn screening programme and/or routine diagnostics.

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